Grimm - S1E8 - Game Ogre

After three murders in this episode, Hank realizes that the victims are all connected to the arrest and conviction of Oleg Stark, who's since escaped and is tracking down those who sentenced him.  In researching his file, Nick discovers that Stark "displays signs of congenital analgesia, a rare genetic disorder which deadens the nerve endings, making it difficult to process pain" and has "abnormally dense" bones:

Later Nick discovers that Stark is a Siegbarste, which Monroe describes as "your basic ogre."

It's significant that his last name is Stark - the German word for strong.  Stark's deadened nerve endings and dense bones seem to contribute to his strength.  At the very least, they help to increase his persistence.

I think it's also significant that that characteristic is his last name.  It's sort of the opposite of the word Grimm.  In the show, it seems that the Grimm Brothers' last name has become the appellation of those who can see Wesen.