During a video call near the beginning of the episode, the Jeffersonian team and Agent Booth receive details about the possible biological contamination to which they've been exposed. Although they're all in the same room, only one or two characters are visible in each shot, and throughout the scene, every character is shown alone at least once:
These shots illustrate the characters' isolation, both generally (they're all confined to the lab) and individually (each character is now unable to spend Christmas with those he or she had planned to spend it with).
Later, there's a shot whose composition seems meant deliberately to contrast with these. In a rather artificial arrangement (as if posed for the camera's benefit), the characters are sitting on one side of a table, so that they're all viewed more or less equally:
Instead of the separation of the previous shots, there's a sense of togetherness here, and this also matches the plot: during this time of confinement, the characters have learned more about each other and grown closer.
Additionally, multiple aspects of this shot (the framing, the characters' positions, and its presentation of a meal) resemble Leonardo da Vinci's The Last Supper:
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